Package: ruminate Title: A Pharmacometrics Data Transformation and Analysis Tool Version: 0.4.0 Authors@R: person("John", "Harrold", , "john.m.harrold@gmail.com", role = c("aut", "cre"), comment = c(ORCID = "0000-0003-2052-4373")) Description: Exploration of pharmacometrics data involves both general tools (transformation and plotting) and specific techniques (non-compartmental analysis). This kind of exploration is generally accomplished by utilizing different packages. The purpose of 'ruminate' is to create a 'shiny' interface to make these tools more broadly available while creating reproducible results. Currently there are modules for uploading one or more datasets, data wrangling, plot genreation, non-compartmental analysis, construction of ODE-based models, and constructing and running adaptive trial simualtions. Analyses can be saved and reloaded later. It's possible to create workflows to automate analyses. There is integrated reporting in Word, Powerpoint and Excel. You can also generate scripts to replicate what was done in the app to create a stand-alone script to run in validated environments. License: BSD_2_clause + file LICENSE BugReports: https://github.com/john-harrold/ruminate/issues URL: https://ruminate.ubiquity.tools/ Encoding: UTF-8 Depends: R (>= 4.2.0) Imports: digest, dplyr, DT, flextable, formods (>= 0.2.0), ggplot2, onbrand (>= 1.0.8), PKNCA (>= 0.10.2), plotly (>= 4.11.0), rhandsontable, rlang, shiny, shinyAce, shinyWidgets, stats, stringr, tidyr, utils, zip Suggests: babelmixr2(>= 0.1.8), cli, clipr, gridExtra, knitr, nlmixr2lib(>= 0.3.0), nonmem2rx, nlmixr2(>= 3.0.4), prompter, rmarkdown, readxl, rxode2 (>= 3.0.0), shinybusy, shinydashboard, shinytest2, testthat (>= 3.0.0), ubiquity Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.3 Config/testthat/edition: 3 VignetteBuilder: knitr Config/pak/sysreqs: libcairo2-dev cmake libfontconfig1-dev libfreetype6-dev libfribidi-dev make libharfbuzz-dev libicu-dev libjpeg-dev libpng-dev libtiff-dev libuv1-dev libwebp-dev libxml2-dev libssl-dev libx11-dev zlib1g-dev Repository: https://john-harrold.r-universe.dev Date/Publication: 2026-02-11 04:55:23 UTC RemoteUrl: https://github.com/john-harrold/ruminate RemoteRef: HEAD RemoteSha: 2b58cceec27d0ed72f243dc2f27bb45f1aa737b2 NeedsCompilation: no Packaged: 2026-06-11 09:30:30 UTC; root Author: John Harrold [aut, cre] (ORCID: ) Maintainer: John Harrold