Changes in version 0.4.0 - Implemented manual point flagging to allow: censoring, exclusion of points from half-life calculation, or specyfing points to use in half-life calcualtion. - Fixed typos in PKNCA parameters (sparse_se -> sparse_auc_se and sparse_df -> sparse_auc_df) - Updated model selection in MDL to include grouping. - Added searchable dependencies table under the App Info tab. - DM: Added data management (DM) module to default apps. - NCA: Moving checksum calculation to separate functions. - Chagned simulate_subjects() to use dataframes and rbind() instead of event tables and etRbind() and it's much faster now Changes in version 0.3.2 (2025-11-04) - Fixed bug in simulate_rules() that prevented proper reset of initial conditions. - Fixed bug in simulate_rules() that prevented tracking of rule evaluation for individuals. Changes in version 0.3.1 (2025-01-10) - CRAN release for MB module to build ODE-based models with rxode2 - CRAN release for CTS module to construct and run rule-based/adaptive trial simulations - Fix for rxode 3.0 release. - Using new yaml save methodology for formods, and will break previous saved states - Added preload() and mk_preload() files - Updated templates/ruminate.R and templates/ruminate_development.R apps to use the preload file in the unzipped analysis state. Changes in version 0.2.4 (2024-05-28) - Fixed issue where changes in data views was leading to PH appearing in the NCA data source selection - Added sparse test dataset Changes in version 0.2.3 (2024-05-18) - Added default naming of NCA analysis from datasets - Added searching in selection of NCA parameters - Fixed sparse sampling in NCA - Added CTS (Clinical trial simulator) module (in development) Changes in version 0.2.2 (2024-03-14) - Fixed error in default ruminate app causing it to crash - Separated ruminate.R sample app into two separate (the default one and one for developent.) Changes in version 0.2.1 (2023-12-11) - Fixed use of suggests that were not conditional. Changes in version 0.2.0 (2023-12-02) - Added MB (model builder) module with (in development) - Support for rxode2 and NONMEM models - Fixed bug in NCA module where column details didn't update properly when switching between analyses. - Fixed bug where detecting dosing from rows left the dosing records in the data frame for subsequent NCA. - Fixed bug where the same parameter(s) were added over the same interval resulting in [[numeric]] in the reported values. Now if the same time interval is added more than once subsequent additions will update the parameters of the interval. - Fixed stand-alone code generation and copy clipboard. Changes in version 0.1.1 (2023-08-29) - Initial release